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Naltrexone is approved to treat alcohol and opioid dependence. Bupropion qualifies to treat depression and seasonal affective disorder so when an aid to stopping smoking treatment.'Obesity continues to be a major public health concern,' said Jean-Marc Guettier, M.D., director with the Division of Metabolism and Endocrinology Products in FDA's Center for Drug Evaluation and Research. 'When used as directed in combination which has a healthy lifestyle that features a reduced-calorie diet and exercise, Contrave provides another treatment choice for chronic weight reduction for people who are obese or are overweight and still have at least one weight-related health.'The drug's effectiveness was evaluated in multiple many studies that included approximately 4,500 obese and overweight patients with and without significant weight-related conditions treated first year. All patients received lifestyle modification that contains a reduced- calorie diet and regular exercise. Results from a clinical trial that enrolled patients without diabetes demonstrated that patients had the average weight loss of 4.1% in contrast to participants have been given placebos) throughout a 12- month period, while another study involving patients with diabetes type 2 symptoms had an average weight loss of 2% over treatment with placebo at one year. Using two separate drugs to shed pounds can be very effective you can find combinations before the FDA now awaiting approval. When dealing with weight reduction and the those who go through it you should err on the side of caution and let the FDA do its job and demand some study be done so the public is aware of the side effects and dangers of the medications before we drive them. Keep in mind that drug companies will be in business to earn money and that they would say anything to keep people on their medications. Researchers found that participants using this drug for the year, dropped excess weight within a month and have kept the extra weight off through the 56 weeks of the study. Contrave is really a combination from the drugs naltrexone and bupropion, which usually reflect a brand new trend of weight-loss drugs that are made up of several active ingredient, that might make them more efficient and safer. Combo-pilling may be the newest fad or also the newest into the future under scrutiny and for that reason it is just more publicly known although in the past, comb-pilling for weight loss has been around since the eighties. The biggest reason that utilizing a combination of pills is now popular will be the fact that as of right now there aren't any long term prescription slimming capsules that have been approved by the FDA besides orlistat. The truly disturbing part is that doctors are prescribing these combinations of medications although some people might of the combinations are already rejected or have yet to be authorized by the FDA. Seizures are a side effect with Contrave and must not be taken in individuals with seizure disorders. The drug can also raise blood pressure and heartrate, and mustn't be used in individuals with a history of heart attack or stroke in the last six months. Blood pressure and pulse should also be measured before beginning the drug and throughout therapy with all the drug. The FDA also warned that Contrave can raise blood pressure and heart rate and must not be used in patients with uncontrolled high blood pressure levels, in addition to by you aren't heart-related and cerebrovascular (circulation system dysfunction impacting your brain) disease. Patients with a history of cardiac arrest or stroke in the last six months, life-threatening arrhythmias, or congestive heart failure were excluded from your clinical trials. Those taking Contrave must have their heart-rate and pulse monitored regularly. In addition, since the compound includes bupropion, Contrave comes with a boxed warning to alert medical professionals and patients on the increased risk of suicidal thoughts and behaviors associated with antidepressant drugs. The warning also notes that serious neuropsychiatric events happen to be reported in patients taking bupropion for quitting smoking. BioCorRx, Inc.'s naltrexone implant is not any bigger than a thumb and is also inserted beneath the patient's skin through a 30-minute, minimally invasive outpatient procedure produced by a medical expert. The implant is administered within BioCorRx, Inc.'s Start Fresh Program which can be distributed in a number of states by independent rehabilitation facilities.